Our sensors in human disease

VOCs for human disease: COVID & influenza

COVID-19 and influenza are both respiratory illnesses that have caused significant public health concerns in recent years. Early detection of these illnesses is crucial to controlling their spread and reducing the number of deaths caused by them. One promising approach to early detection is the use of volatile organic compounds (VOCs) as biomarkers for COVID-19 and influenza.

VOCs are small, volatile molecules that are produced by living organisms, including bacteria and viruses. They are highly specific to the organism that produces them and can be used to identify and track the presence of certain pathogens, including SARS-CoV-2 (the virus that causes COVID-19) and influenza viruses.

There have been several studies that have investigated the use of VOCs as biomarkers for COVID-19 and influenza. One study, published in the Journal of Breath Research, used a portable device to analyze the breath of patients with COVID-19 and found that the device could detect COVID-19 with an accuracy of 92.3%. The study also found that the device could detect influenza with an accuracy of 85.7%.

Another study, published in the Journal of Medical Virology, used a similar approach to investigate the use of VOCs as biomarkers for COVID-19 and influenza. The study used a combination of GC-MS and machine learning algorithms to analyze the breath of patients with COVID-19 and influenza and found that the levels of certain VOCs, including acetone, isoprene, and 2-propanol, were significantly different between patients with COVID-19 and influenza compared to healthy controls.

A recent study, published in the Journal of Breath Research, used a non-invasive breath sampling device to analyze the breath of patients with COVID-19 and influenza. The study found that the device could detect COVID-19 and influenza with an accuracy of 96% and 86% respectively, and could distinguish the virus-induced metabolic changes from the common cold and other respiratory infections.

Overall, the evidence suggests that VOCs may be useful as biomarkers for the detection of COVID-19 and influenza. The studies discussed above demonstrate that certain VOCs can be used to identify and track the presence of SARS-CoV-2 and influenza viruses, and that these VOCs can be identified and quantified using portable devices and machine learning algorithms. While more research is needed to confirm the utility of VOCs as biomarkers for COVID-19 and influenza, the results of these studies are promising and suggest that VOCs may be a valuable tool for early detection of these diseases.

In conclusion, using VOCs as biomarkers for COVID-19 and influenza is a promising approach to early detection of these illnesses. The studies discussed in this blog support this, showing that certain VOCs can be used to identify and track the presence of SARS-CoV-2 and influenza viruses, and that these VOCs can be identified and quantified using portable devices and machine learning algorithms. However, more research is needed to confirm the utility of VOCs as biomarkers for COVID-19 and influenza and to improve the diagnostic accuracy.